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Case Reports and Images in Surgery

 
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Pure non-bilharzial squamous cell carcinoma: An unusual form of carcinoma of the bladder
Fatima Safini1, Hassan Jouhadi2, Meriem Elbachiri1, Souha Sahraoui2, Abdellatif Benider3
1Doctor, Department of Oncology and Radiotherapy, Mohammed VI Cancer Treatment Center, IbnRochd University Hospital, Casablanca, Morocco.
2Associate professor, Department of Oncology and Radiotherapy, Mohammed VI Cancer Treatment Center, IbnRochd University Hospital, Casablanca, Morocco.
3chef of the Department of Oncology and Radiotherapy, Mohammed VI Cancer Treatment Center, IbnRochd University Hospital, Casablanca, Morocco.

Article ID: 100017Z12FS2016
doi:10.5348/Z12-2016-17-CS-9

Address correspondence to:
Fatima Safini
Doctor, Department of Oncology and Radiotherapy, Mohammed VI Cancer Treatment Center
IbnRochd University Hospital
Casablanca
Morocco 20100

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How to cite this article:
Safini F, Jouhadi H, Elbachiri M, Sahraoui S, Benider A. Pure non-bilharzial squamous cell carcinoma: An unusual form of carcinoma of the bladder. J Case Rep Images Surg 2016;2:31–35.


Abstract
Introduction: Non-bilharzial squamous cell carcinoma (NBSCC) is an uncommon form of bladder cancer. In spite of the therapeutic progress, this malignancy is still aggressive with poor prognosis. We systematically reviewed our experience with squamous cell carcinoma of bladder within a period of five years.
Case Series: We performed a retrospective study on seven patients with pure NBSCC of the bladder treated at our radiotherapy and oncology department from 2008 to 2012. A male predominance was observed. The average age at diagnosis was 58 years. The average consultation time was one year. The reason for consultation was hematuria among the seven patients. All of them underwent cystoscopy with biopsy. All the cases displayed muscle invasive carcinoma with a staging of at least T3. Radical cystectomy was the chosen treatment in three cases. Adjuvant treatment was conducted for three patients by receiving either postoperative local irradiation or chemotherapy. Two patients had received an exclusive combined radio-chemotherapy (cisplatin and pelvic irradiation of 60 Gy). Two patients had received palliative care.
Conclusion: Our data show the individuality and poor prognosis of squamous cell cancerous lesions of the urinary tract. The optimal treatment of pure NBSCC of the bladder is not conclusively codified. Further studies are fundamentally in order to optimize the treatment of patients with this rare urological tumor entity.

Keywords: Bladder cancer, Non-bilharzial, Squamous cell carcinoma


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Author Contributions:
Fatima Safini – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hassan Jouhadi – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Meriem Elbachiri – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Souha Sahraoui – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Abdellatif Benider – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Fatima Safini et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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