Journal of

Case Reports and Images in Pathology

 
     
Case Report
 
Neutrophilic eccrine hidradenitis during treatment of acute myeloid leukemia
Wajd Ahmed Althakfi1, Henri Sevestre1, Caroline Delette2
1Department of Surgical Pathology and Cytology, Center University Hospital of Amiens, France
2Department of Hematoncology, Center University Hospital of Amiens, France

Article ID: 100014Z11WA2017
doi:10.5348/Z11-2017-14-CR-3

Address correspondence to:
Wajd Ahmed Althakfi
CHU Amiens-Picardie site Nord
1 place Victor Pauchet
Amiens-80000
France

Access full text article on other devices

  Access PDF of article on other devices

[HTML Full Text]   [PDF Full Text] [Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar]

How to cite this article:
Althakfi WA, Sevestre H, Delette C. Neutrophilic eccrine hidradenitis during treatment of acute myeloid leukemia. J Case Rep Images Pathol 2017;3:9–12.


ABSTRACT

Introduction: Neutrophilic eccrine hidradenitis (NEH) is a rare and benign condition, which belongs to the spectrum of neutrophilic dermatoses. In this paper, we present a case of NEH during administration of chemotherapy for the treatment of acute myeloid leukemia along with histological and clinical findings.
Case Report: This paper presents the case of a 69-year-old male with a history of ulcerative colitis, dyslipidemia, and hypertension. He was diagnosed with acute myeloid leukemia. From day-1 of admission until day-7, the patient was administered cytarabine 200 mg/m2. In addition, idarubicin (12 mg/m2) was initiated on day-3. On day-21, a morbilliform, diffused, pruritic, infiltrated rash was observed. A fresh cutaneous biopsy revealed that these lesions were of viral origin or reaction, without signs of malignant proliferation. The periodic acid Schiff coloration test was negative for infection. The lesions regressed spontaneously after the introduction of amphotericin B and vancomycin.
Conclusion: We concluded that neutrophilic eccrine hidradenitis is self-limiting and non-life-threatening. However, early diagnosis of the condition is necessary to avoid unwarranted medication and surgery. Neutrophilic eccrine hidradenitis can be successfully managed with the use of topical or systemic corticosteroids. Analgesics may be useful in case of pain. Dose adjustment or changing the chemotherapeutic agent is recommended to avoid possible recurrence.

Keywords: Dyslipidemia, Hypertension, Neutrophilic dermatoses, Neutrophilic eccrine hidradenitis, Ulcerative colitis

[HTML Full Text]   [PDF Full Text]

Author Contributions
Wajd Ahmed Althakfi – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Henri Sevestre – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Caroline Delette – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Wajd Ahmed Althakfi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



  Home line About the Journal line Aim and Scope line Open Access line Archives
Apply as Editor line Apply as Reviewer line Submit Reviews - Editors line Submit Reviews - Reviewers
Instructions for Authors line Templates to Use line Copyright Form line Author Checklist
Online Submission line Email Submission line Submit Revision line Submit All Forms line Submit Page Proofs
Terms of Service line Privacy policy line Disclaimer line FAQ line Contact: Journal line Contact: Edorium Journals line Site Map
 
  Copyright © 2017. Edorium. All rights reserved.