Case Series
 
Treatment of early chronic infections with tumor prosthesis by intermittent negative pressure wound therapy with instillation
Yalçın Turhan1, Korhan Özkan2, Esat Uygur3, Murat Demiroğlu4, Bülent Erol5, Hüseyin Çoban6
1Assistant Professor, Orthopedics and Traumatology Department, Duzce University Medical Faculty, Duzce, Turkey
2Professor, Orthopedics and Traumatology Department, Medeniyet University Medical Faculty, Istanbul, Turkey
3Assistant Professor, Orthopedics and Traumatology Department, Medeniyet University Medical Faculty, Istanbul, Turkey
4MD, Orthopedics and Traumatology Department, Medeniyet University Medical Faculty, Istanbul, Turkey
5Professor, Orthopedics and Traumatology Department, Marmara University Medical Faculty, Istanbul, Turkey
6MD, Infectious Diseases and Clinical Microbiology, ELAB, Istanbul, Turkey

Article ID: 100055Z10YT2018
doi: 10.5348/100055Z10YT2018CS

Corresponding Author:
Yalçın Turhan
Medical Faculty of Duzce University
Department of Orthopaedics and Traumatology
Konuralp Street, Center, Duzce, Turkey

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How to cite this article
Turhan Y, Özkan K, Uygur E, Demiroğlu M, Erol B, Çoban H. Treatment of early chronic infections with tumor prosthesis by intermittent negative pressure wound therapy with instillation. J Case Rep Images Oncology 2018;4:100055Z10YT2018.


ABSTRACT

Introduction: Vacuum-assisted closure (VAC) has been used to manage nearly every type of wound seen in orthopedic field including early prosthetic hip and knee infections. In this study, we aimed to present our treatment results of two patients with total and proximal femoral mega prosthesis respectively.

Case Series: With the diagnosis of periprosthetic infection, in both cases, prosthesis were disassembled and sterilized in autoclave. Prosthesis were reimplanted after sterilization and Vacuum Assisted Closure system with instillation. Patients were successfully treated and no signs of infection were detected until ten to twelve months postoperatively.

Conclusion: Mega prosthetic infections pose a great challenge to an orthopedic surgeon and the patient. Besides its economic cost, it causes significant morbidity to the patient. Intermittent negative pressure wound therapy with instillation may be promising technique for the treatment of devastating infections associated with tumor prosthesis.

Keywords: Infection, Instillation, Megaprosthesis, Vacuum assisted closure


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Author Contributions
Yalçın Turhan – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Korhan Özkan – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published
Esat Uygur – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Murat Demiroğl – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published
Bülent Erol – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hüseyin Çoban – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of Submission
The corresponding author is the guarantor of submission.
Source of Support
None
Consent Statement
Written informed consent was obtained from the patient for publication of this case series.
Conflict of Interest
Author declares no conflict of interest.
Copyright
© 2018 Yalçın Turhan et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.