Journal of

Case Reports and Images in Oncology

 
     
Case Report
 
Epithelioid hemangioendothelioma arising from the brachial artery
Niharika Shah1, Karki Smriti2
1MD Pathology, Assistant Professor, Department of Pathology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal
2MD Pathology, Professor, Department of Pathology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal

Article ID: 100037Z10NS2017
doi:10.5348/Z10-2017-37-CR-8

Address correspondence to:
Niharika Shah,
Department of Pathology
B.P.Koirala Institute of Health Sciences, Ghopa Camp
Dharan, Nepal

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How to cite this article:
Shah N, Smriti K. Epithelioid hemangioendothelioma arising from the brachial artery. J Case Rep Images Oncology 2017;3:35–38.


ABSTRACT
Introduction: Weiss and Enzinger first described epithelioid hemangioendothelioma (EHE), a rare vascular tumor, in 1982 as a clinical state between hemangioma and angiosarcoma.
Case Report: We present here a 40-year-old female with complains of pain and swelling over the right arm since five years. Intraoperative findings revealed a mass arising from the brachial artery. Histopathological examination, revealed, proliferation of chains and cords of epithelioid endothelial cells distributed in a myxohyaline stroma. The cells had eosinophilic cytoplasm containing vacuoles that deformed the cytoplasm. Some vacuoles contained fragmented erythrocytes. On immunohistochemistry, the tumor cells were positive for CD 34. A final histopathological diagnosis of epithelioid hemangioendothelioma (low grade) was made. .
Conclusion: Epithelioid hemangioendotheliomas, especially primary vascular ones, are extremely rare, with 33 cases reported in English literature. Surgery seems to be the only beneficial treatment, with a doubtful role of chemotherapy and none for radiotherapy.

Keywords: Brachial artery, CD34, Epithelioid hemangioendothelioma


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Author Contributions
Niharika Shah – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Karki Smriti – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Niharika Shah et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.


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