Journal of

Case Reports and Images in Oncology

 
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Case Report
 
Diagnosis and treatment of concurrent lymphomatosis cerebri and testicular lymphoma
Jia-Ling Chou1, Charles Chau2
1MD, PhD. Southern California Permanente Medical Group, Medical Oncology, 5601 De Soto Avenue, Woodland Hills, CA.
2MD, Southern California, Permanente Medical Group, Radiology, 5601 De Soto Avenue, Woodland Hills, CA.

Article ID: 100022Z10JC2016
doi:10.5348/Z10-2016-22-CR-13

Address correspondence to:
Jia-Ling Chou
MD, PhD, Southern California Permanente Medical Group
Medical Oncology, 5601 De Soto Avenue
Woodland Hills, CA 91365-4084

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How to cite this article:
Jia-Ling C, Chau C. Diagnosis and treatment of concurrent lymphomatosis cerebri and testicular lymphoma. J Case Rep Images Oncology 2016;2:52–56.


Abstract
Introduction: Lymphomatosis cerebri is uncommon. It often poses a diagnostic challenge and carries a poor prognosis. Concurrent testicular lymphoma with lymphomatosis cerebri is even rarer.
Case Report: A case of concurrent lymphomatosis cerebri and testicular lymphoma is presented. Gene arrangement studies helped to establish the diagnosis of lymphomatosis cerebri. Prior to treatment, the patient was bed-bound and confused. He completely recovered his function following intrathecal methotrexate and rituximab in addition to systemic therapy. It was the first report that intrathecal therapy was employed to treat successfully lymphomatosis cerebri. He subsequently tolerated the standard treatment for testicular lymphoma.
Conclusion: It is feasible to treat both lymphomatosis cerebri and testicular lymphoma to achieve remission.

Keywords: Intrathecal therapy, Lymphomatosis cerebri, Testicular lymphoma


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Author Contributions
Jia-Ling Chou – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Charles Chau – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Jia-Ling Chou et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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