Journal of

Case Reports and Images in Oncology

 
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Case Report
 
Unilateral isolated choroidal metastasis secondary to squamous cell carcinoma of uterine cervix
Siddanna R. Palled1, Nihanthy D. S.2, Richa Tiwari2, Surekha Goyal2
1Associate Professor in Radiation Oncology, Kidwai Memorial Institute of oncology, Bangalore, India.
2Resident in Radiation Oncology, Kidwai Memorial Institute of oncology, Bangalore, India.

Article ID: 100019Z10SP2016
doi:10.5348/Z10-2016-19-CR-10

Address correspondence to:
Nihanthy D. S.
#15/32, 6th B cross, 2nd C main road
RMV II Stage, Bhoopsandra New Ext, Sanjay Nagar
Bangalore; Karnataka
India, 560094

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How to cite this article:
Palled SR, Nihanthy DS, Tiwari R, Goyal S. Unilateral isolated choroidal metastasis secondary to squamous cell carcinoma of uterine cervix. J Case Rep Images Oncology 2016;2:38–41.


Abstract
Introduction: Cervical cancer is the fourth most common cancer of women worldwide. It spreads either by local invasion or by hematogenous spread. Metastases to the eye, intraocular metastasis have been reported but they are uncommonly seen. Choroidal secondaries are the most common intraocular malignancies in adults, metastasis to the choroid from utero-cervical carcinoma are an exceedingly rare manifestation.
Case Report: A 50-year-old female, known case of squamous cell carcinoma of uterine cervix stage IIIB, post concurrent chemoradiation treated seventeen months back, presented with complaints of unilateral right sided progressive visual impairment since 15 days. After thorough ophthalmic evaluation and fundoscopic examination multiple choroidal masses and posterior exudative retinal detachment were seen in the right eye. Left eye was normal. Hence, diagnosis of choroidal metastasis of right eye was established. Planned on palliative RT and received a dose of 40 Gy in 20 fractions. Result: A month later, there was marginal improvement in the vision of affected eye.
Conclusion: The case report demonstrates an unusual but possible site of occurrence of metastasis for uterine cervical cancers. The posterior choroid is highly susceptible to disseminated tumor cells compared to the other uveal structures due to its rich vascularity. Orbital metastasis is suggestive of progressive disease, hence early diagnosis and early intervention can save the vision and thus improve the quality of life of the patient.

Keywords: Cervical carcinoma, Chemotherapy, Choroidal metastasis, Radiotherapy, Squamous cell carcinoma


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Author Contributions
Siddanna R. Palled – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Nihanthy D. S. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Richa Tiwari – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Surekha Goyal – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Siddanna R. Palled et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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