Journal of

Case Reports and Images in Oncology

 
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Case Report
 
Incidentally detected superior mediastinal thymoma: An interesting case report
Suhag V.1, Sunita B.S.2, Sarin A.3, Dutta V.4, Singh A.K.5
1Lt Col Virender Suhag, HOD Radiation Oncology, Army Hospital (R&R) Delhi-110010 (India).
2Lt Col Sunita BS, MD DNB Pathology Classified Specialist Base Hospital, Delhi-110010 (India).
3Surg Cmde Arti Sarin, Consultant Radiodiagnosis and Radiotherapy, HOD Oncology Centre, Command Hospital (SC), Pune, India.
4Brig Vibha Dutta, SM, Consultant Pathology and Oncopathology, HOD Pathology and Lab Sciences, Army Hospital (R&R) Delhi-110010 (India).
5Col AK Singh, Senior Advisor Radio-diagnosis and Imaging, Army Hospital (R&R) Delhi-110010 (India).

Article ID: 100012Z10SV2016
doi:10.5348/Z10-2016-12-CR-3

Address correspondence to:
Lt Col Virender Suhag
MD DNB, HOD Radiation Oncology Army Hospital (R&R) Delhi-110010
(India)

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How to cite this article:
Suhag V, Sunita BS, Sarin A, Dutta V, Singh AK. Incidentally detected superior mediastinal thymoma: An interesting case report. J Case Rep Images Oncology 2016;2:9–13.


Abstract
Introduction: Thymic malignancies represent a wide range of clinical, histological and molecular entities, with considerable heterogeneity even among tumors of the same histotype. Thymomas are rare neoplasms arising from tissue elements of the thymus and developing in the anterior mediastinum, with an annual incidence of only 0.15 cases per 100, 000 person-years. They can be associated with a variety of systemic and autoimmune disorders, such as pure red cell aplasia, pancytopenia, hypogammaglobulinemia, collagen-vascular disease, and most commonly with myasthenia gravis. Surgical resection remains the cornerstone of therapy for early-stage disease, while in advanced or recurrent forms, a multimodality approach incorporating radiation and chemotherapy is required. Platinum with anthracycline-based chemotherapy is an optimal combination for advanced thymoma.
Case Report: We herein present an interesting case of thymoma which was detected on imaging for routine health check-up and was managed successfully by surgery and adjuvant radiotherapy.
Conclusion: A high index of suspicion and thorough evaluation of any mediastinal mass picked up on routine imaging is of paramount importance for early detection of thymomas.

Keywords: Mediastinum, Radiotherapy, Surgery, Thymoma


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Author Contributions
Suhag V. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sunita B.S. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Sarin A. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Dutta V. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Singh A.K. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Suhag V. et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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