Journal of

Case Reports and Images in Obstetrics and Gynecology

 
     
Case Report
 
Ovarian metastasis of gastrointestinal stromal tumor: A case report and review of the literatures
Mayumi Kobayashi1, Hiroshi Yoshida2, Reiko Watanabe2, Tomoyasu Kato4
1MD, Division of Gynecology, National Cancer Center Hospital, Tokyo, Japan
2MD, PhD, Departments of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan

Article ID: 100023Z08MK2017
doi: 10.5348/Z08-2017-23-CR-3

Address correspondence to:
Hiroshi Yoshida
MD, PhD, Department of Pathology and Clinical Laboratories
National Cancer Center Hospital, 5-1-1 Tsukiji Chuouku
Tokyo
Japan

Access full text article on other devices

  Access PDF of article on other devices

[HTML FULL TEXT]   [PDF Full Text] [Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar]

How to cite this article:
Kobayashi M, Yoshida H, Watanabe R, Kato T. Ovarian metastasis of gastrointestinal stromal tumor: A case report and review of the literatures. J Case Rep Images Gynecol Obstet 2017;3:9–12.


ABSTRACT
Introduction: Ovarian metastases of gastrointestinal stromal tumors (GISTs) are extremely rare, however, these patients may still have a favorable prognosis when treated with imatinib after resection.
Case Report: We report on the successful treatment of a 54-year-old female with gastric GIST metastatic to the ovary, who had undergone distal gastrectomy 11 years ago. The resected ovarian tumor was a solid multinodular mass consisting of KIT-positive and discovered on gastrointestinal stromal tumors protein (DOG1)-positive spindle cells, and was thus diagnosed as a recurrent metastasis of gastric GIST. No tumor recurrence was observed during the two years of follow-up while on imatinib therapy.
Conclusion: As GIST metastatic to the ovary may mimic primary ovarian tumors, KIT and DOG1 immunohistochemistry can aid in making correct pathological diagnosis. Furthermore, patients with this particular metastatic pattern may benefit from imatinib treatment after resection.

Keywords: Gastrointestinal stromal tumor, Kitt, Metastasis, Ovary


[HTML FULL TEXT]   [PDF Full Text]

Acknowledgements
We acknowledge Editage’s editorial support in preparing this manuscript.

Author Contributions
Mayumi Kobayashi – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hiroshi Yoshida – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Reiko Watanabe – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Tomoyasu Kato – Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Mayumi Kobayashi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



  Home line About the Journal line Aim and Scope line Open Access line Archives
Apply as Editor line Apply as Reviewer line Submit Reviews - Editors line Submit Reviews - Reviewers
Instructions for Authors line Templates to Use line Copyright Form line Author Checklist
Online Submission line Email Submission line Submit Revision line Submit All Forms line Submit Page Proofs
Terms of Service line Privacy policy line Disclaimer line FAQ line Contact: Journal line Contact: Edorium Journals line Site Map
 
  Copyright © 2017. Edorium. All rights reserved.