Journal of

Case Reports and Images in Obstetrics and Gynecology

 
     
Case Report
 
Primary ovarian choriocarcinoma masquerading as ruptured ectopic pregnancy in an HIV positive woman
Rachel M Whynott1, Julie Vitko2, Shelly W Holmstrom3, Meredith Gray4
1MD, Resident, Department of Obstetrics and Gynecology, University of South Florida, Tampa, FL, USA.
2MD, Ruffolo, Hooper & Associates MD PA, Consultants in Pathology & Laboratory Medicine, Tampa, FL, USA.
3MD, Associate Professor, The University of South Florida Morsani College of Medicine, Department of Obstetrics and Gynecology, Tampa, FL, USA.
4MD, Assistant Professor, Department of Obstetrics and Gynecology, University of Kansas, Kansas City, MO, USA.

Article ID: 100022Z08RW2017
doi:10.5348/Z08-2017-22-CR-2

Address correspondence to:
Rachel M. Whynott
MD, The University of South Florida Morsani College of Medicine, Department of Obstetrics and Gynecology
Tampa General Circle
6th Floor STC, Tampa
FL 33606

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How to cite this article:
Whynott RM, Vitko J, Holmstrom SW, Gray M. Primary ovarian choriocarcinoma masquerading as ruptured ectopic pregnancy in an HIV positive woman. J Case Rep Images Gynecol Obstet 2017;3:5–9.


Abstract
Introduction: Ovarian choriocarcinoma is a highly malignant and rare gynecologic tumor. This cancer should be considered in the differential diagnosis of women presenting with a suspected ectopic pregnancy.
Case Report: A multiparous HIV positive woman presented with a suspected ruptured chronic ectopic pregnancy. Her final pathology demonstrated choriocarcinoma arising out of an ovarian ectopic pregnancy versus a primary choriocarcinoma of the ovary. Further evaluation showed metastases to her brain and lungs. Despite aggressive chemotherapy, the patient continued to have progressive physical and mental decline. She was discharged to hospice care during her last admission to our institution and subsequently died.
Conclusion: Ovarian choriocarcinoma should be considered when evaluating women with a ectopic pregnancy, especially in the setting of the human immunodeficiency virus.

Keywords: Choriocarcinoma, Ectopic, HIV, Pregnancy, Trophoblastic


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Author Contributions
Rachel M. Whynott – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Julie Vitko – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Shelly W. Holmstrom – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Meredith Gray – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Rachel M. Whynott et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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