Journal of

Case Reports and Images in Medicine

 
     
Case Series
 
Heterotopic ossification: A case series
Donald Hamby1, Brian Chau1, Mickey Lui2, Calvin Fesler3, Sarah Humbert4, Scott Strum5, Brian Kim6
1MD, Resident Physician, Department of Physical Medicine and Rehabilitation, Loma Linda University.
2DO, Resident Physician, Department of Physical Medicine and Rehabilitation, Loma Linda University.
3Medical Student, Loma Linda University.
4MD, Assistant Professor of Neurology and Physical Medicine and Rehabilitation, Loma Linda University.
5MD, Associate Professor of Physical Medicine and Rehabilitation, Loma Linda University.
6Medical Student, Loma Linda University.

Article ID: 100028Z09DH2016
doi:10.5348/Z09-2016-28-CS-21

Address correspondence to:
Calvin Reed Fesler
1400 Barton Road, #311, Redlands
CA
USA, 92373

Access full text article on other devices

  Access PDF of article on other devices

[HTML Full Text]   [PDF Full Text] [Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar]

How to cite this article:
Hamby D, Chau B, Lui M, Fesler C, Humbert S, Strum S, Kim B. Heterotopic ossification: A case series. J Case Rep Images Med 2016;2:89–94.


Abstract
Heterotopic ossification is an underrecognized condition of uncertain etiology encountered by many physicians in the acute setting with pain and fever as common presenting symptoms. When pain and fever occur in the setting of swelling, erythema and/or decreased joint mobility, heterotopic ossification can present like cellulitis, osteomyelitis, thrombophlebitis, and tumor along with many other infectious and rheumatologic phenomena. A high degree of suspicion is required in patients at risk for heterotopic ossification. Although the pathophysiology of this condition is yet to be fully elucidated, certain risk factors have been identified. We present five cases of patients who developed heterotopic ossification secondary to variety of predisposing conditions: traumatic brain injury (TBI), spinal cord injury (SCI), stroke, and lower limb amputation. Management was a combination of pain control and bisphosphonate therapy in addition to range of motion exercises with skilled therapists. These cases demonstrate the heterogeneity of conditions that may predispose individuals to the development of heterotopic ossification and highlight the importance of considering such a diagnosis in order to achieve early treatment so as to prevent functional loss and progression that may require more aggressive intervention.

Keywords: Bone, Brain injury, Heterotopic ossification, Spinal cord, Trauma


[HTML Full Text]   [PDF Full Text]

Author Contributions:
Donald Hamby – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Brian Chau – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Mickey Lui – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Calvin Fesler – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sarah Humbert – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Scott Strum – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Brian Kim – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Donald Hamby et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



  Home line About the Journal line Aim and Scope line Open Access line Archives
Apply as Editor line Apply as Reviewer line Submit Reviews - Editors line Submit Reviews - Reviewers
Instructions for Authors line Templates to Use line Copyright Form line Author Checklist
Online Submission line Email Submission line Submit Revision line Submit All Forms line Submit Page Proofs
Terms of Service line Privacy policy line Disclaimer line FAQ line Contact: Journal line Contact: Edorium Journals line Site Map
 
  Copyright © 2017. Edorium. All rights reserved.