Journal of

Case Reports and Images in Medicine

 
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Case Report
 
Head injury as a trigger of Parry-Romberg syndrome: A case report and review of etiology
Saad Azim1, Jamal Janjua1, Azer Majeed1, Sidra Zahoor1
1Department of Medicine, Khan Research Laboratories (KRL) Hospital, Islamabad, 44000, Pakistan.

Article ID: 100012Z09SA2016
doi:10.5348/Z09-2016-12-CR-5

Address correspondence to:
Jamal Janjua
House No. 687, Chaudhry Walayat Ali Khan Road
Chaklala Scheme 3, Rawalpindi
Pakistan, Postal Code 44000

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How to cite this article:
Azim S, Janjua J, Majeed A, Zahoor S. Head injury as a trigger of Parry-Romberg syndrome: A case report and review of etiology. J Case Rep Images Med 2016;2:15–19.


Abstract
Introduction: This is a case of a patient with the rare entity of Parry-Romberg syndrome (PRS) which discuss the etiological association with preceding head trauma as well as the possible therapeutic role of vitamin B12, with a brief review of literature.
Case Report: A 22-year-old female presented with a history of head injury preceding the progressive onset of right-sided facial pain and atrophy, evident facial asymmetry with periorbital hyperpigmentation on the right side of the face, enophthalmos and watering of the right eye. Laboratory investigations revealed a low vitamin B12 level. A final diagnosis of Parry-Romberg syndrome ("progressive hemifacial atrophy") was based on clinical and a radiological examination.
Conclusion: Parry-Romberg syndrome is an incompletely understood self-limiting degenerative condition, characterized by unilateral atrophic changes of the face. The pathophysiology of the syndrome remains unclear, but the etiologic relevance of factors like head injury and vitamin B12 deficiency needs to be investigated in further collective studies.

Keywords: Etiology, Head injury, Hemi facial atrophy, Parry-Romberg syndrome, Scleroderma


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Author Contributions
Saad Azim – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jamal Janjua – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Azer Majeed – Substantial contributions to conception and design, Acquisition of data, Drafting the article, revising it critically for important intellectual content, Final approval of the version to be published
Sidra Zahoor – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Saad Azim et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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